PLAyground in Alzheimer's

Playground injuries in children

BACKGROUND Rapid urbanization and unplanned population development can be detrimental to the safety of citizens, with children being a particularly vulnerable social group. In this review, we assess childhood playground injuries and suggest safety mechanisms which could be incorporated into playground planning. METHODS Inclusion criteria were "children" as the focus group, "playground" as the...

Order in the playground

In eukaryotes the arrangement of genes along the chromosome is not as random as it at first appeared, and distinctive clusters of functionally related but non-homologous genes can be found in the genomes of certain animals and fungi. These include the major histocompatibility complex in mammals and gene clusters for nutrient use and secondary metabolite production in fungi. A growing number of ...

Effects of hyperoxia in alzheimers transgenic mice

Glucose Role in Treatment of Alzheimers’ Disease

1. Dong H, Csernansky JG (2009) Effects of Stress and Stress Hormones on Amyloidβ Protein and Plaque Deposition. J Alzheimers Dis 18: 459-469. 2. Csernansky JG, Dong H, Fagan AM, Wang L, Xiong C, et al. (2006) Plasma cortisol and progression of dementia in subjects with Alzheimer‐ type dementia. Am J Psychiatry 163: 2164-2169. 3. Swaab DF, Raadsheer FC, Endert E, Hofman MA, Kamphorst W, et al. ...

Severity of playground-related fractures: more than just playground factors?

INTRODUCTION Despite the establishment of playground safety standards, playground-related injuries are still a significant cause of extremity fractures in Singapore. This prospective study evaluates the dimensions and characteristics of our playgrounds, and their effect on fracture severity in an Asian population. We aim to correlate various playground risk factors with severity of the fracture...